Article
[Association of single nucleotide polymorphisms of Nrf2 promoter region with susceptibility to vitiligo].
Zhonghua yi xue za zhi - 8 Apr 2008
Zhou Miao-Ni, Xu Ai-E, Lu Liang-Jun, Li Yong-Wei, Zhao De-Kuang, Guan Cui-Ping
Abstract excerpt
OBJECTIVE: To investigate the association of the single nucleotide polymorphisms (SNPs) in Nrf2 promoter region with the susceptibility to risk of vitiligo. METHODS: Samples of peripheral blood were collected from 300 vitiligo patients and 300 healthy persons. The genotypes of -686A/G, -684G/A, and -650C/A were detected by direct-sequencing. Genotyping of variable number of tandem repeat (VNTR) was performed by...
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