Article
Association of HLA-DQA1 and DQB1 genes with vitiligo in Chinese Hans.
International journal of dermatology - 1 Dec 2005
Yang Sen, Wang Ji-Yun, Gao Min, Liu Hong-Sheng, Sun Liang-Dan, He Ping-Ping, Liu Jiang-Bo, Zhang An-Ping, Cui Yong, Liang Yan-Hua, Wang Zai-Xing, Zhang Xue-Jun
Abstract excerpt
BACKGROUND: Vitiligo is an acquired depigmentary disorder of the skin and hair which results from selective destruction of melanocytes. Serological typing and genotyping of human leukocyte antigen (HLA) have shown discrepancies in HLA associations with vitiligo in different ethnic populations. METHODS: Polymerase chain reaction sequence-specific primer (PCR-SSP) method was used to analyze the distribution of...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Child
- Child, Preschool
- Female
- Gene Frequency
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- HLA-DQ beta-Chains
