Article
Association of polymorphism of IL-10 and TNF-A genes with gastric cancer in Korea.
Cancer letters - 28 Jul 2005
Lee Ja Young, Kim Hak Yang, Kim Kyung Ho, Kim Seong Man, Jang Myoung Kuk, Park Joon Yong, Lee Jin Heon, Kim Jin-Ho, Yoo Jae Young
Abstract excerpt
We performed this study to determine the role of polymorphisms of the IL-10 and TNF-alpha promoter genes in the carcinogenesis/pathogenesis of gastric cancer (GC) and peptic ulcer diseases (PUD) in Korea. A total of 232 patients with gastric diseases and 120 healthy controls were included. Polymorphisms of IL-10-1082/-592 gene and TNF-A-308 gene were genotyped by PCR-RFLP. There were no differences in genotypes...
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