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Morphological changes in tumour type after radiotherapy are accompanied by changes in gene expression profile but not in clinical behaviour

12 Aug 2004

Abstract excerpt

The morphological features of neoplastic cells, combined with a stromal reaction, determine the presence of cancer at the microscopic level. Malignant tumours arise through a series of genetic alterations, but these do not entirely explain invasive and metastatic behaviour and correlate only weakly with morphological changes. In order to understand the relationship between the morphology of cancer tissue, gene...

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PMID: 15378567
DOI: 10.1002/path.1621

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