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Article

The early response of p53-dependent proteins during radiotherapy in human rectal carcinoma and in adjacent normal tissue.

International journal of oncology - 1 Nov 2003

Stift A, Prager G, Selzer E, Widder J, Kandioler D, Friedl J, Teleky B, Herbst F, Wrba F, Bergmann M

Abstract excerpt

The aim of this study was to investigate the activation of the p53 pathway and the induction of apoptosis during preoperative radiotherapy in normal human rectal tissue and in rectal carcinoma. Twelve patients with rectal cancer of the lower third were enrolled in this study. Tumor specimens and adjacent normal tissue were obtained before radiation, after the third radiation cycle and from the surgically removed...

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Source

Identifiers

PMID: 14532965
DOI: 10.3892/ijo.23.5.1269

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MDM2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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