Article

Fractionated radiation alters the extracellular matrix produced by muscle-invasive bladder cancer cells

2025-04-15

Abstract excerpt

Muscle-invasive bladder cancer (MIBC) is a prevalent disease that can be treated with radiotherapy, but has a poor prognosis. Radiation-induced extracellular matrix (ECM) remodelling and fibrosis can induce tumour resistance and recurrence, but has not been studied in MIBC. Here we aimed to characterise the impact of radiation on the ECM composition of MIBC. <h4>Materials and Methods</h4> Three MIBC cell lines (T...

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Literature Corpus work: 6fb25181-c453-5eee-9a0f-a58ba0c5da7c
DOI: 10.1101/2025.04.08.647735

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