Article
Molecular histology in the study of solid tumours.
Molecular pathology : MP - 1 Apr 2002
Campbell R J, Pignatelli M
Abstract excerpt
Dominant oncogenes and tumour suppressor gene abnormalities are crucial events in human cancer. Many molecular techniques are used to identify these abnormalities, including single strand conformational polymorphism, the polymerase chain reaction, cloning, and sequencing, although the biological relevance of these changes is not always apparent. Immuno-histochemistry (ICH) or western blotting of abnormal gene...
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