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Article

Cytokine gene polymorphisms in ischaemic heart disease: investigation using family-based tests of association.

Journal of molecular medicine (Berlin, Germany) - 1 Nov 2004

McGlinchey Paul G, Spence Mark S, Patterson Chris C, Allen Adrian R, Murphy Gillian, Savage David A, Maxwell A Peter, McKeown Pascal P

Abstract excerpt

Atherosclerosis has an inflammatory basis, with cytokines, cellular adhesion molecules and pro-inflammatory cells having important roles in the initiation and progression of this process. Interleukin (IL) 6, IL-10 and transforming growth factor (TGF) beta1 have been proposed as important modulators of the atherosclerotic process, with IL-6 having a pro-inflammatory, atherogenic effect and IL-10 and TGF-beta1...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15378163
DOI: 10.1007/s00109-004-0576-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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