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Article

Topological assignment of the N-terminal extension of plasma gelsolin to the gelsolin surface.

The Biochemical journal - 1 Feb 2005

Fock Ulrike, Jockusch Brigitte M, Schubert Wolf-Dieter, Hinssen Horst

Abstract excerpt

The actin-binding protein gelsolin is highly conserved in vertebrates and exists in two isoforms, a cytoplasmic and an extracellular variant, generated by alternative splicing. In mammals, these isoforms differ only by an N-terminal extension in plasma gelsolin, a short sequence of up to 25 amino acids. Cells and tissues may contain both variants, as plasma gelsolin is secreted by many cell types. The tertiary...

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Identifiers

PMID: 15377282
DOI: 10.1042/BJ20040875
PMCID: PMC1134740

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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