Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BP180/Collagen XVII: A Molecular View

12 Nov 2021

Abstract excerpt

BP180 is a type II collagenous transmembrane protein and is best known as the major autoantigen in the blistering skin disease bullous pemphigoid (BP). The BP180 trimer is a central component in type I hemidesmosomes (HD), which cause the adhesion between epidermal keratinocytes and the basal lamina, but BP180 is also expressed in several non-HD locations, where its functions are poorly characterized. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmune Bullous Skin Diseases
Share to Coagulation, Bradykinin, Polyphosphates, and Angioedema
Share to Urticaria and Related Conditions

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34830116
DOI: 10.3390/ijms222212233

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 18 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BP180/Collagen XVII: A Molecular ViewPMID 34830116Read ↗

BP180/type XVII collagen: its role in acquired and inherited disorders or the dermal-epidermal junctionSemantic proximity Read ↗

Cloning and Primary Structural Analysis of the Bullous Pemphigoid Autoantigen BP180Semantic proximity Read ↗

A homozygous in-frame deletion in the collagenous domain of bullous pemphigoid antigen BP180 (type XVII collagen) causes generalized atrophic benign epidermolysis bullosa.Semantic proximity Read ↗

Deletion of the cytoplasmatic domain of BP180/collagen XVII causes a phenotype with predominant features of epidermolysis bullosa simplex.Semantic proximity Read ↗

Autoreactive T and B cells from bullous pemphigoid (BP) patients recognize epitopes clustered in distinct regions of BP180 and BP230.Semantic proximity Read ↗

Collagen XVII.Semantic proximity Read ↗

BP180 as the common autoantigen in blistering diseases with different clinical phenotypes.Semantic proximity Read ↗

Molecular pathology of the basement membrane zone in heritable blistering diseases:: The paradigm of epidermolysis bullosa.Semantic proximity Read ↗

Enigmatic insight into collagenSemantic proximity Read ↗

Characterization of the anti-BP180 autoantibody reactivity profile and epitope mapping in bullous pemphigoid patients.Semantic proximity Read ↗

Severity and phenotype of bullous pemphigoid relate to autoantibody profile against the NH2- and COOH-terminal regions of the BP180 ectodomain.Semantic proximity Read ↗

Bullous pemphigoid antigen II (BP180) and its soluble extracellular domains are major autoantigens in mucous membrane pemphigoid: the pathogenic relevance to HLA class II alleles and disease severity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.