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Article

Substrate binding analysis of the 23S rRNA methyltransferase RrmJ.

Journal of bacteriology - 1 Oct 2004

Hager Jutta, Staker Bart L, Jakob Ursula

Abstract excerpt

The 23S rRNA methyltransferase RrmJ (FtsJ) is responsible for the 2'-O methylation of the universally conserved U2552 in the A loop of 23S rRNA. This 23S rRNA modification appears to be critical for ribosome stability, because the absence of functional RrmJ causes the cellular accumulation of the individual ribosomal subunits at the expense of the functional 70S ribosomes. To gain insight into the mechanism of...

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Identifiers

PMID: 15375145
DOI: 10.1128/JB.186.19.6634-6642.2004
PMCID: PMC516604

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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