Article
Substrate binding analysis of the 23S rRNA methyltransferase RrmJ.
Journal of bacteriology - 1 Oct 2004
Hager Jutta, Staker Bart L, Jakob Ursula
Abstract excerpt
The 23S rRNA methyltransferase RrmJ (FtsJ) is responsible for the 2'-O methylation of the universally conserved U2552 in the A loop of 23S rRNA. This 23S rRNA modification appears to be critical for ribosome stability, because the absence of functional RrmJ causes the cellular accumulation of the...
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