Article
Overexpression of two different GTPases rescues a null mutation in a heat-induced rRNA methyltransferase.
Journal of bacteriology - 1 May 2002
Tan Jacqueline, Jakob Ursula, Bardwell James C A
Abstract excerpt
The Escherichia coli RrmJ (FtsJ) heat shock protein functions as an rRNA methyltransferase that modifies position U2552 of 23S rRNA in intact 50S ribosomal subunits. An in-frame deletion of the rrmJ (ftsJ) gene leads to severe growth disadvantages under all temperatures tested and causes significant accumulation of ribosomal subunits at the expense of functional 70S ribosomes. To investigate whether...
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