Article
The physiological role of cytotoxic CD4+ T-cells: the holy grail?
31 Aug 2004
Abstract excerpt
From the textbooks, one can readily learn that CD4+ T-cells display a variety of helper functions, necessary for the mounting of an efficient adaptive immune response. Indeed, for about two decades, the study of CD4+ T-cells has been mainly focused on their polarization into T helper 1 or T helper 2 cells and the role of these subpopulations in cellular and humoral immunity, respectively; so that CD4+ T-cells...
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