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Article

Role of CD4 + Cytotoxic T Lymphocytes in the Control of Viral Diseases and Cancer

1 Jul 2010

Abstract excerpt

Our knowledge on the physiological role of CD4(+) T lymphocytes has improved in the last decade: available data convincingly demonstrate that, besides the 'helper' activity, CD4(+) T cells may be also endowed with lytic properties. The cytotoxic function of these effector cells has a relevant role in the control of pathogenic infections and in mediating antitumor immune responses. On these bases, several...

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Identifiers

PMID: 20635880
DOI: 10.3109/08830185.2010.489658

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