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Article

Persistence of mitochondrial toxicity in hearts of female B6C3F1 mice exposed in utero to 3'-azido-3'-deoxythymidine.

Cardiovascular toxicology - 1 Jan 2004

Walker Dale M, Poirier Miriam C, Campen Matthew J, Cook Dennis L, Divi Rao L, Nagashima Kunio, Lund Amie K, Cossey Patsy Y, Hahn Fletcher F, Walker Vernon E

Abstract excerpt

Cardiac toxicity has been associated with HIV infection and exposure to nucleoside reverse transcriptase inhibitors (NRTIs), but the role of the latter in the development of cardiac disease of HIV-infected patients is uncertain. To investigate the cardiotoxicity of transplacentally administered zidovudine (AZT) or AZT plus lamivudine (3TC) in the absence of HIV infection, we evaluated several biomarkers of...

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Identifiers

PMID: 15371630
DOI: 10.1385/ct:4:2:133

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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