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Article

Mitochondrial dysfunction following perinatal exposure to nucleoside analogues

22 Aug 2006

Abstract excerpt

Antiretroviral drugs given during pregnancy and immediately after birth are extraordinarily effective at preventing mother-to-child transmission of HIV-1: the transmission rate is dramatically decreased from 15–20% to less than 1%, at least for women intensively managed with potent antiretroviral therapy [1,2]. Current recommendations are now based on antiretroviral combinations, mostly including at least two...

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PMID: 16931932
DOI: 10.1097/01.aids.0000242814.42344.77

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