Article
In utero exposure of female CD-1 Mice to AZT and/or 3TC: I. Persistence of microscopic lesions in cardiac tissue.
Cardiovascular toxicology - 1 Mar 2010
Torres Salina M, March Thomas H, Carter Meghan M, McCash Consuelo L, Seilkop Steven K, Poirier Miriam C, Walker Dale M, Walker Vernon E
Abstract excerpt
The current study was designed to delineate temporal changes in cardiomyocytes and mitochondria at the light and electron microscopic levels in hearts of mice exposed transplacentally to commonly used nucleoside analogs (NRTIs). Pregnant CD-1 mice were given 80 mg AZT/kg, 40 mg 3TC/kg, 80 mg AZT/...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.