Article

Tetraploidy accelerates adaption under drug-selection in a fungal pathogen

2021-02-28

Abstract excerpt

Baseline ploidy significantly impacts evolutionary trajectories, and in particular, tetraploidy has been associated with higher rates of adaptation compared to haploidy and diploidy. While the majority of experimental evolution studies investigating ploidy use Saccharomyces cerivisiae , the fungal pathogen Candida albicans is a powerful system to investigate ploidy dynamics, particularly in the context of antifu...

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Literature Corpus work: bff92e53-d16e-5f76-be3e-435c95e9df16
DOI: 10.1101/2021.02.28.433243

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