Article

Ploidy determines the consequences of antifungal-induced mutagenesis in Candida albicans, a human fungal pathogen

2019-07-03

Abstract excerpt

Organismal ploidy state and environmental stress impact the mutational spectrum and the mutational rate. The human fungal pathogen Candida albicans , serves as a clinically relevant model for studying the interaction between eukaryotic ploidy and stress-induced mutagenesis. In this study, we compared the rates and types of genome perturbations in diploid and tetraploid C. albicans following exposure to two class...

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Literature Corpus work: da316e22-f572-5466-a24c-061a9fcecc04
DOI: 10.1101/686881

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