Article
GABAA receptor beta 1, beta 2, and beta 3 subunits: comparisons in DBA/2J and C57BL/6J mice.
Biochimica et biophysica acta - 14 Mar 1995
Kamatchi G L, Kofuji P, Wang J B, Fernando J C, Liu Z, Mathura J R, Burt D R
Abstract excerpt
GABAA receptors link binding of GABA (gamma-aminobutyric acid) to inhibitory chloride flux in the brain. They are the site of action of several important classes of drugs, and have been implicated in animal models of epilepsy and in the actions of alcohol. We compare the sequence and expression of the beta 1, beta 2 and beta 3 subunits of GABAA receptors in two inbred strains of mice, DBA/2J and C57BL/6J, which...
Topics
- Alcohol Drinking
- Amino Acid Sequence
- Animals
- Base Sequence
- DNA Mutational Analysis
- DNA, Complementary
- Gene Library
- Genes
- Genetic Predisposition to Disease
- Mice
- Mice, Inbred C57BL
