Article
Differentiating the role of gamma-aminobutyric acid type A (GABAA) receptor subtypes.
Biochemical Society transactions - 1 Jun 2004
Wafford K A, Macaulay A J, Fradley R, O'Meara G F, Reynolds D S, Rosahl T W
Abstract excerpt
The inhibitory tone maintained throughout the central nervous system relies predominantly on the activity of neuronal GABAA (gamma-aminobutyric acid type A) receptors. This receptor family comprises various subtypes that have unique regional distributions, but little is known about the role played by each subtype. The majority of the receptors contain a gamma2 subunit and are sensitive to modulation by BZs...
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