Article
The role of haplotypes in candidate gene studies.
Genetic epidemiology - 1 Dec 2004
Clark Andrew G
Abstract excerpt
Human geneticists working on systems for which it is possible to make a strong case for a set of candidate genes face the problem of whether it is necessary to consider the variation in those genes as phased haplotypes, or whether the one-SNP-at-a-time approach might perform as well. There are three reasons why the phased haplotype route should be an improvement. First, the protein products of the candidate genes...
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