Article
Human cytomegalovirus TRS1 protein is required for efficient assembly of DNA-containing capsids.
Journal of virology - 1 Oct 2004
Adamo Joan E, Schröer Jörg, Shenk Thomas
Abstract excerpt
The human cytomegalovirus tegument protein, pTRS1, appears to function at several discrete stages of the virus replication cycle. We previously demonstrated that pTRS1 acts during the late phase of infection to facilitate the production of infectious virions. We now have more precisely identified the late pTRS1 function by further study of a mutant virus lacking the TRS1 region, ADsubTRS1. We observed a...
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