Article
The VPS4 component of the ESCRT machinery plays an essential role in HPV infectious entry and capsid disassembly
28 Mar 2017
Abstract excerpt
Human Papillomavirus (HPV) infection involves multiple steps, from cell attachment, through endocytic trafficking towards the trans-Golgi network, and, ultimately, the entry into the nucleus during mitosis. An essential viral protein in infectious entry is the minor capsid protein L2, which engages different components of the endocytic sorting machinery during this process. The ESCRT machinery is one such...
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