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Article

Genetic predisposition of the interleukin-6 response to inflammation: implications for a variety of major diseases?

Clinical chemistry - 1 Nov 2004

Bennermo Marie, Held Claes, Stemme Sten, Ericsson Carl-Göran, Silveira Angela, Green Fiona, Tornvall Per

Abstract excerpt

BACKGROUND: A single-nucleotide polymorphism (SNP) in the promoter region of the interleukin-6 (IL-6) gene at position -174 (G>C) has been reported to be associated with a variety of major diseases, such as Alzheimer disease, atherosclerosis, and cardiovascular disease, cancer, non-insulin-dependent diabetes mellitus, osteoporosis, sepsis, and systemic-onset juvenile chronic arthritis. However, authors of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15364891
DOI: 10.1373/clinchem.2004.037531

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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