Article
Analysis of G(-174)C IL-6 polymorphism and plasma concentrations of inflammatory markers in patients with type 2 diabetes and peripheral arterial disease.
Journal of clinical pathology - 1 Feb 2006
Libra M, Signorelli S S, Bevelacqua Y, Navolanic P M, Bevelacqua V, Polesel J, Talamini R, Stivala F, Mazzarino M C, Malaponte G
Abstract excerpt
AIMS: To determine whether the G(-174)C interleukin 6 (IL-6) polymorphism influences the development of peripheral arterial disease (PAD) in individuals with type 2 diabetes. This was investigated by comparing the distribution of G(-174)C genotypes between patients with type 2 diabetes and PAD (PAD+) and those with type 2 diabetes but without PAD (PAD-). Plasma concentrations of IL-6, fibrinogen, C reactive...
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