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Article

Mutation analysis of SHIP gene in acute leukemia.

Zhongguo shi yan xue ye xue za zhi - 1 Aug 2004

Luo Jian-Min, Liu Ze-Lin, Hao Hong-Ling, Wang Fu-Xu, Dong Zuo-Ren, Ohno Ryuzo

Abstract excerpt

The SH2 domain containing inositol 5'-phosphatase (SHIP) was initially described as a 145 kD protein phosphorylated on tyrosines upon growth factor and cytokine stimulation. SHIP is predominately expressed in hematopoietic cells, and is a crucial negative regulator in the development of hematopoietic cells. To evaluate the role of the SHIP gene in human leukemogenesis, expression and mutation of SHIP gene in bone...

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PMID: 15363123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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