Article
Tumour-stroma interactions in carcinogenesis: basic aspects and perspectives.
Molecular and cellular biochemistry - 1 Jun 2004
Kiaris H, Chatzistamou I, Kalofoutis Ch, Koutselini H, Piperi Ch, Kalofoutis A
Abstract excerpt
In contrast to the conventional notion regarding tumour development as a cell autonomous process in which the major participants were the cancer cells, increasing evidence attributes important role in the stromal components, namely fibroblasts, and view the tumour as a heterogenous mixture of different cell types. These different types of cells, being cancer cells, fibroblasts, endothelial cells, and others,...
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