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Article

Co-evolution of tumor cells and their microenvironment.

Trends in genetics : TIG - 1 Jan 2009

Polyak Kornelia, Haviv Izhak, Campbell Ian G

Abstract excerpt

Increasing evidence indicates that tumor-stromal cell interactions have a crucial role in tumor initiation and progression. These interactions modify cellular compartments, leading to the co-evolution of tumor cells and their microenvironment. Although the importance of microenvironmental alterations in tumor development is recognized, the molecular mechanisms underlying these changes are only now beginning to be...

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Identifiers

PMID: 19054589
DOI: 10.1016/j.tig.2008.10.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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