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Article

Visualization of a highly organized intranuclear network of filaments in living mammalian cells.

Cell motility and the cytoskeleton - 1 Oct 2004

Nalepa Grzegorz, Harper J Wade

Abstract excerpt

For 30 years, the mammalian cell nucleus has been hypothesized to contain a filamentous framework, the nuclear matrix or karyoskeleton, which regulates nuclear structure and function. However, such an organized network of filaments has never been observed in living cells. Here we show that human Cdc14B phosphatase in living cells tightly associates with long filaments that begin at the nucleolar periphery and...

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Identifiers

PMID: 15362113
DOI: 10.1002/cm.20023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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