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Article

The dynamism of PABPN1 nuclear inclusions during the cell cycle.

Neurobiology of disease - 1 Sept 2006

Marie-Josée Sasseville A, Caron Antoine W, Bourget Lucie, Klein Arnaud F, Dicaire Marie-Josée, Rouleau Guy A, Massie Bernard, Langelier Yves, Brais Bernard

Abstract excerpt

Oculopharyngeal muscular dystrophy (OPMD) is caused by expansion of a (GCN)10 to a (GCN)11-17 repeat coding for a polyalanine domain at the N-terminal part of poly(A) binding protein nuclear 1 (PABPN1). OPMD is characterized by the presence of intranuclear inclusions (INIs) in skeletal muscle fibers of patients. The formation of GFP-b13AlaPABPN1 INIs and their fate through the cell cycle were followed by...

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Source

Identifiers

PMID: 16860991
DOI: 10.1016/j.nbd.2006.05.015

Genes

PABPN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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