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Article

Analysis of HBsAg mutations in the 25 years after the implementation of the hepatitis B vaccination plan in China.

Virus genes - 1 Oct 2020

Ye Huiming, Teng Jing, Lin Zhiyuan, Wang Ye, Fu Xiaochun

Abstract excerpt

Since 1992, China has promoted hepatitis B vaccination. Concurrently, during this period, increasing use of immunoglobulins and nucleoside analogues might have exerted selective pressure on the hepatitis B virus (HBV) S gene, driving mutations in the HBsAg and changed the subtype. Using the National Center for Biotechnology Information database, we obtained gene sequence information for HBV strains from China and...

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PMID: 32542478
DOI: 10.1007/s11262-020-01773-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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