Article
yTAFII61 has a general role in RNA polymerase II transcription and is required by Gcn4p to recruit the SAGA coactivator complex.
Molecular cell - 1 Nov 1998
Natarajan K, Jackson B M, Rhee E, Hinnebusch A G
Abstract excerpt
We obtained a recessive insertion mutation in the gene encoding yeast TBP-associated factor yTAFII61/68 that impairs Gcn4p-independent and Gcn4p-activated HIS3 transcription. This mutation also reduces transcription of seven other class II genes, thus indicating a broad role for this yTAFII in RN...
Topics
- Acetyltransferases
- Amitrole
- Blotting, Northern
- Cell Division
- DNA-Binding Proteins
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Histone Acetyltransferases
- Hydro-Lyases
- Models, Genetic
- Mutagenesis, Insertional
- Phenotype
- Precipitin Tests
- Protein Binding
- Protein Kinases
- RNA Polymerase II
- Recombinant Fusion Proteins