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Article

Characterization of the 5′-regulatory region of the human thiamin transporter <i>SLC19A3</i>: in vitro and in vivo studies

24 Jun 2004

Abstract excerpt

Transcriptional regulation of expression of the human thiamin transporter-2 (the product of the SLC19A3 gene) is unknown. In this study, we cloned the 5'-regulatory region of the human SLC19A3 gene (2,016 bp), identified the minimal promoter region required for basal activity, demonstrated a critical role for specific cis-regulatory elements in determining the promoter activity, and confirmed activity and...

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PMID: 15217784
DOI: 10.1152/ajpgi.00234.2004

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