Genetic Polymorphism of the Nrf2 Promoter Region (rs35652124) Is Associated with the Risk of Diabetic Foot Ulcers.

doi:10.1155/2020/9825028

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Genetic Polymorphism of the Nrf2 Promoter Region (rs35652124) Is Associated with the Risk of Diabetic Foot Ulcers.

Oxidative medicine and cellular longevity - 1 Jan 2020

Teena Rajan, Dhamodharan Umapathy, Ali Daoud, Rajesh Kesavan, Ramkumar Kunka Mohanram

Abstract excerpt

The genetic polymorphism in the nuclear factor erythroid 2-related factor 2 (Nrf2) gene has been reported as one of the prognosis markers for various diseases, including cancer. Nrf2 is a key transcription factor involved in wound healing by regulating angiogenesis. We investigated the genetic association of NRF2 single-nucleotide polymorphism rs35652124 with T2DM and DFU and assessed its functional impact. A...

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PMID: 32879654
DOI: 10.1155/2020/9825028
PMCID: PMC7448237

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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