Article
Transcriptional upregulation of both egl-1 BH3-only and ced-3 caspase is required for the death of the male-specific CEM neurons.
Cell death and differentiation - 1 Aug 2010
Nehme R, Grote P, Tomasi T, Löser S, Holzkamp H, Schnabel R, Conradt B
Abstract excerpt
Most of the 131 cells that die during the development of a Caenorhabditis elegans hermaphrodite do so approximately 30 min after being generated. Furthermore, in these cells, the pro-caspase proCED-3 is inherited from progenitors and the transcriptional upregulation of the BH3-only gene egl-1 is...
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