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Article

The TRA-1A sex determination protein of C. elegans regulates sexually dimorphic cell deaths by repressing the egl-1 cell death activator gene.

Cell - 6 Aug 1999

Conradt B, Horvitz H R

Abstract excerpt

The hermaphrodite-specific neurons (HSNs) of the nematode Caenorhabditis elegans are generated embryonically in both hermaphrodites and males but undergo programmed cell death in males. The gene egl-1 encodes a BH3-containing cell death activator that is required for programmed cell death in C. e...

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Caenorhabditis
Caenorhabditis elegans Proteins
Disorders of Sex Development
DNA, Helminth
Helminth Proteins
Luminescent Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oligodeoxyribonucleotides

Sex Determination Processes

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Identifiers

PMID: 10458607
DOI: 10.1016/s0092-8674(00)81961-3

Genes

TRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-10458607-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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