Article
Evidence for positive selection on Mycobacterium tuberculosis within patients.
BMC evolutionary biology - 9 Sept 2004
Tanaka Mark M
Abstract excerpt
BACKGROUND: While the pathogenesis and epidemiology of tuberculosis are well studied, relatively little is known about the evolution of the infectious agent Mycobacterium tuberculosis, especially at the within-host level. The insertion sequence IS6110 is a genetic marker that is widely used to track the transmission of tuberculosis between individuals. This and other markers may also facilitate our understanding...
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