Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluating the contributions of purifying selection and progeny-skew in dictating within-host Mycobacterium tuberculosis evolution.

Evolution; international journal of organic evolution - 1 May 2020

Morales-Arce Ana Y, Harris Rebecca B, Stone Anne C, Jensen Jeffrey D

Abstract excerpt

The within-host evolutionary dynamics of tuberculosis (TB) remain unclear, and underlying biological characteristics render standard population genetic approaches based upon the Wright-Fisher model largely inappropriate. In addition, the compact genome combined with an absence of recombination is expected to result in strong purifying selection effects. Thus, it is imperative to establish a biologically relevant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Evolution
Share to Evolution and Genetic Dynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Genetic

Share to Mutation

Share to Mycobacterium research and diagnosis

Share to Mycobacterium tuberculosis

Share to Selection, Genetic

Share to Tuberculosis Research and Epidemiology

Source

Open in PubMed Open full text

Identifiers

PMID: 32233086
DOI: 10.1111/evo.13954
PMCID: PMC9546059

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluating the contributions of purifying selection and progeny-skew in dictating within-host Mycobacterium tuberculosis evolution.PMID 32233086Read ↗

Within-host <i>Mycobacterium tuberculosis</i> evolution: a population genetics perspectiveSemantic proximity Read ↗

Within Host Evolution Selects for a Dominant Genotype of Mycobacterium tuberculosis while T Cells Increase Pathogen Genetic Diversity.Semantic proximity Read ↗

The Role of Selection in Shaping Diversity of Natural M. tuberculosis PopulationsSemantic proximity Read ↗

The within-host population dynamics of Mycobacterium tuberculosis vary with treatment efficacy.Semantic proximity Read ↗

Bottlenecks and broomsticks: the molecular evolution of Mycobacterium bovis.Semantic proximity Read ↗

Sampling Bias in the Molecular Epidemiology of TuberculosisSemantic proximity Read ↗

Genetic drift and within-host metapopulation dynamics of HIV-1 infectionSemantic proximity Read ↗

Evidence for positive selection on Mycobacterium tuberculosis within patients.Semantic proximity Read ↗

Comparing epidemic tuberculosis in demographically distinct heterogeneous populations.Semantic proximity Read ↗

Transition bias influences the evolution of antibiotic resistance in Mycobacterium tuberculosisSemantic proximity Read ↗

The Influence of HIV on the Evolution of Mycobacterium tuberculosis.Semantic proximity Read ↗

Historical Intensity of Natural Selection for Resistance to TuberculosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.