Article
Context-sensitive transposition of IS6110 in mycobacteria.
Microbiology (Reading, England) - 1 Nov 1999
Wall Sue, Ghanekar Kiran, McFadden Johnjoe, Dale Jeremy W
Abstract excerpt
The rational use of IS6110 fingerprinting for studies of the molecular epidemiology and evolution of Mycobacterium tuberculosis requires understanding of the dynamics of transposition. In laboratory model systems, it has been shown that transposition is context-sensitive, i.e. it is influenced by the nature of the site in which the insertion sequence is presented. Stimulation of transposition by activation of an...
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