Article
The tumor necrosis factor-alpha promoter -1031C polymorphism is associated with decreased risk of endometriosis in a Japanese population.
Human reproduction (Oxford, England) - 1 Nov 2004
Asghar Tasneem, Yoshida Shigeki, Kennedy Stephen, Negoro Kenichi, Zhuo Wang, Hamana Shinya, Motoyama Satoru, Nakago Satoshi, Barlow David, Maruo Takeshi
Abstract excerpt
BACKGROUND: Tumor necrosis factor-alpha (TNF-alpha) is a multifunctional proinflammatory cytokine, associated with various inflammatory and autoimmune diseases. Elevated TNF-alpha levels in peritoneal fluid have been reported in women with endometriosis, suggesting that TNF-alpha may be involved in the development of endometriosis. In this study, we investigated the possible association between endometriosis and...
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