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Article

Novel patterns of nevirapine resistance-associated mutations of human immunodeficiency virus type 1 in treatment-naïve patients.

Virology - 1 Oct 2004

Hachiya Atsuko, Gatanaga Hiroyuki, Kodama Eiichi, Ikeuchi Mieko, Matsuoka Masao, Harada Shigeyoshi, Mitsuya Hiroaki, Kimura Satoshi, Oka Shinichi

Abstract excerpt

Several reports have recently shown that drug-resistant human immunodeficiency virus type 1 (HIV-1) is often isolated from treatment-naïve patients. We phenotypically analyzed HIV-1 strains isolated from 44 treatment-naïve individuals and found two strains highly resistant (69- and >310-fold) against nevirapine (NVP). Direct sequencing showed these two isolates had a novel mutation, K238S, in reverse...

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Identifiers

PMID: 15351209
DOI: 10.1016/j.virol.2004.07.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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