Article
Rapid screening of phenotypic resistance to nevirapine by direct analysis of HIV type 1 reverse transcriptase activity in plasma.
AIDS research and human retroviruses - 1 Sept 1999
Vázquez-Rosales G, García Lerma J G, Yamamoto S, Switzer W M, Havlir D, Folks T M, Richman D D, Heneine W
Abstract excerpt
Drug susceptibility testing for the clinical management of human immunodeficiency virus type 1 (HIV-1)-infected persons is often curtailed because such testing is expensive and time consuming. We describe a non-culture-based phenotypic assay for the rapid analysis of HIV-1 resistance to nevirapine. The assay measures the susceptibility of plasma reverse transcriptase (RT) activity to inhibition by nevirapine by...
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