Article
Patterns of resistance mutations selected by treatment of human immunodeficiency virus type 1 infection with zidovudine, didanosine, and nevirapine.
The Journal of infectious diseases - 1 Mar 2000
Hanna G J, Johnson V A, Kuritzkes D R, Richman D D, Brown A J, Savara A V, Hazelwood J D, D'Aquila R T
Abstract excerpt
Resistance mutations selected in reverse transcriptase (RT) by incompletely suppressive therapy with combination zidovudine and didanosine with or without nevirapine were identified in 141 human immunodeficiency virus type 1 isolates from peripheral blood mononuclear cells of 57 individuals in the AIDS Clinical Trials Group protocol 241. After prolonged treatment (16-48 weeks), the most common nevirapine-selected...
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