Article
Spectrum of Non-Nucleoside Reverse Transcriptase Inhibitor-Associated Drug Resistance Mutations in Persons Living with HIV-1 Receiving Rilpivirine.
Viruses - 31 Oct 2024
Nagarajan Pavithra, Zhou Jinru, Di Teodoro Giulia, Incardona Francesca, Seguin-Devaux Carole, Kaiser Rolf, Abecasis Ana B, Gomes Perpetua, Tao Kaiming, Zazzi Maurizio, Shafer Robert W
Abstract excerpt
INTRODUCTION: Few data are currently available on the nonnucleoside reverse transcriptase (RT) inhibitors (NNRTI) resistance mutations selected in persons living with HIV-1 (PLWH) who develop virological failure while receiving rilpivirine (RPV). METHODS: We analyzed pooled HIV-1 RT genotypic data from 280 PLWH in the multicenter EuResist database and 115 PLWH in the Stanford HIV Drug Resistance Database (HIVDB)...
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