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Article

Characterization of a nuclear localization signal in the C-terminus of the adeno-associated virus Rep68/78 proteins.

Virology - 1 Oct 2004

Cassell Geoffrey D, Weitzman Matthew D

Abstract excerpt

Adeno-associated virus (AAV) replicates in the nucleus of infected cells, and therefore multiple nuclear import events are required for productive infection. We analyzed nuclear import of the viral Rep proteins and characterized a nuclear localization signal (NLS) in the C-terminus. We demonstrate that basic residues in this region constitute an NLS that is transferable and mediates interaction with the nuclear...

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Identifiers

PMID: 15351208
DOI: 10.1016/j.virol.2004.06.034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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