Article
Screening of virulence traits in Legionella pneumophila and analysis of the host susceptibility to infection by using the Dictyostelium host model system.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009
Shevchuk Olaga, Steinert Michael
Abstract excerpt
The social soil amoeba Dictyostelium discoideum has been established as a host model for several human pathogens including Legionella pneumophila. The complete genome sequence, the genetic tractability, and the phagocytic characteristics of Dictyostelium generate many opportunities for the study of host-pathogen interactions. Important applications of this haploid model organism are (i) the use of Dictyostelium...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
