Article
Cross talk between sphingolipids and glycerophospholipids in the establishment of plasma membrane asymmetry.
Molecular biology of the cell - 1 Nov 2004
Kihara Akio, Igarashi Yasuyuki
Abstract excerpt
Glycerophospholipids and sphingolipids are distributed asymmetrically between the two leaflets of the lipid bilayer. Recent studies revealed that certain P-type ATPases and ATP-binding cassette (ABC) transporters are involved in the inward movement (flip) and outward movement (flop) of glycerophospholipids, respectively. In this study of phytosphingosine (PHS)-resistant yeast mutants, we isolated mutants for...
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