Article
The Rim101 pathway is involved in Rsb1 expression induced by altered lipid asymmetry.
Molecular biology of the cell - 1 May 2008
Ikeda Mika, Kihara Akio, Denpoh Aki, Igarashi Yasuyuki
Abstract excerpt
Biological membranes consist of lipid bilayers. The lipid compositions between the two leaflets of the plasma membrane differ, generating lipid asymmetry. Maintenance of proper lipid asymmetry is physiologically quite important, and its collapse induces several cellular responses including apoptosis and platelet coagulation. Thus, a change in lipid asymmetry must be restored to maintain "lipid asymmetry...
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