Article
Regulation of yeast nutrient permease endocytosis by ATP-binding cassette transporters and a seven-transmembrane protein, RSB1.
The Journal of biological chemistry - 12 Nov 2010
Johnson Soraya S, Hanson Pamela K, Manoharlal Raman, Brice Sarah E, Cowart L Ashley, Moye-Rowley W Scott
Abstract excerpt
Ceramide is produced by the condensation of a long chain base with a very long chain fatty acid. In Saccharomyces cerevisiae, one of the two major long chain bases is called phytosphingosine (PHS). PHS has been shown to cause toxicity in tryptophan auxotrophic strains of yeast because this bioactive ceramide precursor causes diversion of the high affinity tryptophan permease Tat2 to the vacuole rather than the...
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